QSAR (Quantitative Structure Activity Relationship) is an estimating method to predict the values from the quantitative correlation between chemical structure and physicochemical properties, based on the knowledge that the similar chemical structure has similar chemical characteristic.

Also grouping of substances and read-across is one of the most commonly used alternative approaches for filling data gaps in registrations. US and EU are very conservative of performing the animal test for chemical substances to protect animal welfare. Furthermore, the cost and the time taken for toxicity test are very heavy burden to industry. Therefore, QSAR and read-across approach are very active research field, especially for pre-screening stage of physical properties and toxicity. For EPA, this technique and its knowledge have been accumulated well. In EU, REACH started in June 2007 has accepted QSAR and Read-across data for physicochemical properties and toxicity data. In K-REACH, the public notice for registration has the item for the chemicals with submission of similar structural chemical data

Chemtopia's consulting service

Chemtopia provides estimation service for physicochemical properties and various toxicological data using QSAR and read-across approach to predict the below information so it helps saving cost for industry on toxicity test.